论文部分内容阅读
目的调查我国妊娠滋养细胞疾病(gestationaltrophoblasticdisease,GTD)的发生情况,为防治本病提供依据。方法联合我国浙江、江苏、福建、安徽、江西、山西和河南7省143所医院,对1991—2000年间GTD的发生情况进行调查。结果删除因填表有缺项的单位,实际统计了7省118所医院的资料,妊娠总数为3674654例,GTD为14222例,占387‰。GTD中,葡萄胎9194例,占646%;侵蚀性葡萄胎3452例,占243%;绒毛膜癌1521例,占107%;胎盘部位滋养细胞肿瘤55例,占04%。葡萄胎中完全性葡萄胎7079例,占770%,部分性葡萄胎2115例,占230%。GTD发病年龄多在20~34岁,占855%。结论本调查以医院为调查单位,葡萄胎的发生率较20世纪50年代有明显下降趋势。临床上需重视GTD的病理诊断,及完全性葡萄胎和部分性葡萄胎的诊断。
Objective To investigate the occurrence of gestational trophoblastic disease (GTD) in our country and provide basis for the prevention and treatment of this disease. Methods A total of 143 hospitals in 7 provinces of Zhejiang, Jiangsu, Fujian, Anhui, Jiangxi, Shanxi and Henan provinces of China were surveyed to investigate the incidence of GTD between 1991 and 2000. Results Deleted due to fill in the missing units, the actual statistical data of 118 hospitals in 7 provinces, the total number of pregnancy was 3674654 cases, GTD was 14222 cases, accounting for 387 ‰. GTD, hydatidiform mole 9194 cases, accounting for 646%; 3452 cases of invasive mole, accounting for 243%; chorionic cancer 1521 cases, accounting for 107%; placental trophoblastic tumor in 55 cases, accounting for 04%. Complete hydatidiform mole in 7079 cases, accounting for 770%, 2115 cases of partial mole, accounting for 230%. GTD onset age in 20 to 34 years old, accounting for 855%. Conclusions The survey was conducted on a hospital-by-patient basis. The incidence of hydatidiform mole was significantly lower than that of the 1950s. Clinic should pay attention to the pathological diagnosis of GTD, and complete hydatidiform mole and partial hydatidiform mole diagnosis.