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目的研究小剂量米非司酮在子宫肌瘤患者的治疗中的应用效果。方法以收治的100例子宫肌瘤患者为对象,随机分为观察组和对照组两组,对照组采用丹那唑治疗,观察组采用小剂量米非司酮联合丹那唑治疗,治疗3个月停药,随访6个月,对比分析两组患者治疗前后血红蛋白水平、子宫肌瘤体积以及用药时间和不良反应等数据。结果两组患者治疗后,血红蛋白水平及子宫肌瘤体积均有明显改善,观察组改善幅度远大于对照组,治疗有效率高于对照组。两组患者均未因药物发生不良反应。结论对于子宫肌瘤患者应用小剂量米非司酮是一种安全有效的理想治疗方法,临床效果显著,值得广泛应用。
Objective To study the effect of low dose mifepristone in the treatment of patients with uterine fibroids. Methods One hundred cases of uterine fibroids were treated and divided into observation group and control group randomly. The control group was treated with danazol, the observation group was treated with low dose mifepristone plus Danazol, and the treatment was stopped for 3 months Drugs, followed up for 6 months, comparative analysis of two groups of patients before and after treatment hemoglobin levels, uterine fibroids volume and medication time and adverse reactions and other data. Results After treatment, hemoglobin level and uterine fibroids volume were significantly improved in both groups. The improvement rate in the observation group was much larger than that in the control group, and the treatment efficiency was higher than that in the control group. Two groups of patients did not cause adverse reactions due to drugs. Conclusion The application of low dose mifepristone in patients with uterine fibroids is a safe and effective method of treatment. The clinical effect is significant and should be widely used.