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目的:对无明显心血管病(CVD)临床症状者的高甘油三酯(TG)≥1.60 mmol/L低高密度脂蛋白胆固醇(HDL-C)≤1.18 mmol/L伴有活动平板运动试验(TET)心电图(ECG)阳性和TET ECG阴性的缺血性心脏病(IHD)的危险因素进行了对比观察。方法:对无明显CVD临床症状的2900例受试者检测TG/HDL-C、其中伴有TET ECG阳性(缺血型ST-T改变)者500例和TET ECG阴性(不伴有缺血型ST-T改变)者2500例进行了5年对比观察,预测其预后。结果:在5年随访的观察中高TG(≥1.60 mmol/L)/低HDL-C(≤1.18 mmmol/L)伴有TET ECG阳性者500例的IHD的发生(30例)率为6.00%;IHD死亡(14例)率为2.80%。而高TG/低HDL-C TET ECG阴性者2500例的IHD发生(25例)率为2.80%,死亡(8例)率为0.32%,P<0.001。表明高TG/低HDL-C伴有TET ECG阳性者是IHD的较大危险因素。结论:高TG/低H DL-C,伴有TET ECG阳性对IHD者的死亡率的预测有重要意义,提示二者指标共同作用对IHD者极为不利。
OBJECTIVE: To investigate the relationship between high-triglyceride (TG) ≥1.60 mmol / L and high-density lipoprotein cholesterol (HDL-C) ≤1.18 mmol / L in patients without obvious clinical symptoms of cardiovascular disease TET) electrocardiogram (ECG) positive and TET ECG negative ischemic heart disease (IHD) risk factors were compared. Methods: Totally 500 patients with TET-positive ECG (ischemic ST-T change) and TET-ECG negative (without ischemic ST-T changes) 2500 cases were compared for 5 years to predict the prognosis. Results: The incidence of IHD (500 cases) was 6.00% in 500 cases with high TG (≥1.60 mmol / L) / low HDL-C (≤1.18 mmol / L) and TET ECG positive at 5 years of follow - IHD death (14 cases) was 2.80%. In 2500 cases with high TG / low HDL-C TET ECG negative, the incidence of IHD was 2.80% (25 cases) and the death rate (8 cases) was 0.32% (P <0.001). High TG / low HDL-C with TET ECG positive were the major risk factors for IHD. CONCLUSION: The predictive value of high TG / low H DL-C and TET ECG positive for IHD is of great significance in predicting the mortality of IHD, suggesting that the combination of the two indicators is extremely unfavorable to IHD.