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目的:研究临床早期子宫内膜癌腹膜后淋巴结转移的相关因素,为子宫内膜癌有选择实施腹膜后淋巴结切除寻找依据。方法:回顾分析2012年6月至2017年3月于我院行手术治疗的335例临床早期子宫内膜癌患者的术后病理资料,采用卡方检验进行单因素分析,Logistic回归进行多因素分析。结果:335例临床早期子宫内膜癌中,24例腹膜后淋巴结转移,淋巴结转移率7.16%。单因素分析提示,子宫肌层浸润深度、宫颈管浸润、脉管癌栓与早期子宫内膜癌的腹膜后淋巴结转移有关;Logistic多因素分析提示,宫颈管累及、脉管癌栓是临床早期子宫内膜癌腹膜后淋巴结转移的独立高危因素。结论:宫颈管浸润和脉管癌栓是早期子宫内膜癌腹膜后淋巴结转移的重要高危因素,是早期子宫内膜癌实施腹膜后淋巴结切除的重要依据。
Objective: To study the related factors of retroperitoneal lymph node metastasis in early stage of endometrial cancer, and to find out the basis for selective retroperitoneal lymph node dissection for endometrial cancer. Methods: The postoperative pathological data of 335 patients with early stage endometrial cancer undergoing surgery in our hospital from June 2012 to March 2017 were retrospectively analyzed. One-factor analysis was performed by chi-square test and multivariate analysis was performed by Logistic regression . Results: Among the 335 cases of early clinical endometrial cancer, 24 cases had retroperitoneal lymph node metastasis and lymph node metastasis rate of 7.16%. Univariate analysis showed that the depth of myometrial invasion, cervical canal invasion, vascular thrombosis and retroperitoneal lymph node metastasis of early endometrial cancer were related. Logistic multivariate analysis showed that cervical canal involvement and vascular thrombosis were early clinical uterus Endometrial cancer patients with retroperitoneal lymph node metastasis of independent risk factors. Conclusion: Cervical duct infiltration and vascular thrombosis are important risk factors of early retroperitoneal lymph node metastasis of endometrial cancer and an important basis for resection of retroperitoneal lymph node in early stage of endometrial cancer.