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为了了解长期接触氟化物对骨代谢及钙、镁、锌、铜元素的影响，对某铝厂电解车间３５例工人血清骨钙素、碱性磷酸酶、钙、镁元素及铜、锌水平进行了检测，并与同厂３７例非暴露氟化物者进行了对照分析。结果发现，实验组血清骨钙素、钙、镁水平均低于对照组，差异具有显著意义（Ｐ＜０．０１，Ｐ＜０．０５，Ｐ＜０．０１）。提示长期氟暴露可能影响骨形成过程。但两组血清碱性磷酸酶及铜、锌水平差异无显著意义（Ｐ值均大于０．０５）。
In order to understand the impact of long-term exposure to fluoride on bone metabolism and calcium, magnesium, zinc and copper, serum osteocalcin, alkaline phosphatase, calcium, magnesium and copper and zinc in 35 workers in an aluminum plant electrolysis workshop The test, and with the same factory 37 cases of non-exposed fluoride were controlled analysis. The results showed that the serum osteocalcin, calcium and magnesium levels in the experimental group were lower than those in the control group (P <0.01, P <0.05, P <0.01). Prompted long-term fluoride exposure may affect bone formation. However, serum alkaline phosphatase and copper, zinc levels were no significant difference (P values were greater than 0.05).