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摘要目的采用以鼠多发性硬化(MS)建立的实验性自身免疫脑脊髓炎(EAE)模型,评价髓过氧化物酶(MPO)作为较新治疗目标,双-5-羟色胺-二乙烯三胺五乙酸-钆(MPO-Gd)作为影像学标记物,在MS等脱髓鞘疾病中的作用。材料与方法动物实验由学院动物保护委员会批准。采用蛋白脂质蛋白质(PLP)于
Abstract Objective To evaluate the efficacy and safety of myeloperoxidase (MPO) as a new therapeutic target in experimental autoimmune encephalomyelitis (EAE) model established by multiple sclerosis (MS) in rats. Bis-5-hydroxytryptamine- The Role of MPO-Gd as Imaging Markers in Demyelinating Diseases such as MS. Materials and Methods Animal experiments were approved by the College Animal Protection Committee. The use of protein lipoprotein (PLP) in