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目的 观察前列腺癌患者内分泌治疗前后前列腺的 MRI表现。 方法 分析 3 6例前列腺癌患者内分泌治疗前后前列腺体积的变化和信号的变化。 结果 3 6例经内分泌治疗后其前列腺体积平均缩小 ( 3 3 .5± 1 9.6) % ( P<0 .0 1 ) ,其中周围带体积缩小程度〔( 55.8± 2 3 .3 ) %〕大于移行带缩小程度〔( 2 9.3± 2 2 .0 ) %〕( P<0 .0 5) ;同时 ,在 T2加权像上前列腺周围带及移行带信号均显示不同程度的弥漫性减低 ;前列腺体积缩小与血清前列腺特异抗原 ( PSA)水平下降之间有显著性相关( r=0 .67,P<0 .0 5)。 结论 前列腺癌内分泌治疗后 MRI的表现为前列腺和精囊的体积缩小 ,信号减低。
Objective To observe the MRI findings of prostate in patients with prostate cancer before and after endocrine therapy. Methods The changes of prostate volume and signal before and after endocrine therapy in 36 patients with prostate cancer were analyzed. Results The average volume of prostate in 3 6 cases (33.5 ± 1 9.6%) after endocrine therapy was reduced (P <0.01) (2 9.3 ± 22.0)%] (P <0.05). At the same time, the signals around the prostate and the transitional zone on the T2-weighted images all showed diffuse reduction in varying degrees; the volume of the prostate There was a significant correlation between reduction and serum PSA (r = 0.67, P <0.05). Conclusion The appearance of MRI after endocrine therapy of prostate cancer is that the volume of prostate and seminal vesicle is reduced and the signal is decreased.