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目的:分析戊型肝炎病毒感染患者的血清学生化特征;为HEV的临床诊治和进一步研究提供参考。方法:收集2007年8月～2008年8月间HEV感染患者667例的相关血清学生化指标进行回顾性资料分析比较。结果:HEV感染病例多分布在21岁～40岁年龄段;且女性多于男性。在HEV阳性患者中,青少年组与青年组、中年组,老年组在ALP项差异具有统计学意义。老年组HEV感染患者的各项指标都处于较高水平。结论:HEV主要侵犯青壮年,老年人的肝功能损害比年轻人严重;HEV阳性女性患者所占比例较多,戊型肝炎病毒感染后AST、ALT增高。
Objective: To analyze the serological characteristics of patients with hepatitis E virus infection and to provide a reference for the clinical diagnosis and further study of HEV. Methods: A retrospective data analysis was performed on 667 cases of HEV infection between August 2007 and August 2008. Results: The cases of HEV infection were mostly distributed in the age group of 21 to 40 years old, and there were more women than men. Among HEV-positive patients, there was significant difference in ALP between adolescent group and young group, middle-aged group and elderly group. Elderly patients with HEV infection in the indicators are at a high level. CONCLUSIONS: HEV mainly affects young adults. The elderly patients have severe hepatic impairment compared with young people. HEV-positive women account for a large proportion of patients, and hepatitis E and AST increase after infection.