论文部分内容阅读
作者以80只小鼠移植肝癌为模型,对其随机分为对照组及5个不同剂量的治疗组.对治疗组瘤内注射~(90)Y玻璃微球(~(90)Y GM),并观察疗效,探寻有效治疗剂量.结果表明当瘤内给予1～3mci/cm~3 剂量的~(90)Y时,肿瘤坏死或严重变性而无明显副作用.术后5天测定的肿瘤重量治疗组与对比组间差异显著(P<0.001);而治疗组间比较则无显著差异(P>0.05).
The authors transplanted liver cancer into 80 mice as a model. They were randomly divided into a control group and five different doses of treatment groups. Intratumoral injection of ~(90)Y glass microspheres (~(90)Y GM) was performed on the treatment group. Observe the curative effect and explore the effective therapeutic dose. The results showed that when intracranial administration of ~ (30%) Mm/cm~3 dose of ~ (90) Y, the tumor necrosis or severe degeneration without obvious side effects. The weight of the tumor measured after 5 days of operation There was significant difference between the group and the control group (P<0.001), but there was no significant difference between the treatment groups (P>0.05).