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本文报道造血系统恶性肿瘤死亡而行尸检的61例,其中用抗癌剂者(化疗组)46例(男25例,女21例,平均年龄58岁),行骨髓移植者(移植组)15例(男13例,女2例,平均年龄27岁)。化疗组中急性髓性白血病(AML)17例,急性淋巴细胞白血病(ALL)6例,慢性髓性白血病(CML)2例,恶性淋巴瘤(ML)14例,多发性骨髓瘤(MM)7例。移植组中AML4例,ALL6例,CML4例,ML1例。所有病例光镜检查示肝中心静脉闭塞(VOD)及高度狭窄者诊断为VOD。轻型患者仅肝组织检查为VOD,从临床症状难以确诊。重型患者临床有腹水。肝组织学检查结果:61例中16例(26%)有VOD。化疗组46例中10例(22%)有VOD,其中轻型8例,重型2例;移植组15
This article reports 61 cases of hematopoietic malignant tumor death and autopsy, of which 46 cases (25 males and 21 females, mean age 58 years) were treated with anti-cancer agent (chemotherapy group), and bone marrow transplant recipients Example (13 males and 2 females, mean age 27 years). Seventeen patients with acute myeloid leukemia (AML), six with acute lymphoblastic leukemia (ALL), two with chronic myelogenous leukemia (CML), 14 with malignant lymphoma (ML), and 7 with multiple myeloma example. In the transplantation group, there were 4 cases of AML, 6 cases of ALL, 4 cases of CML and 1 case of ML. Light microscopic examination of all cases showed central venous occlusion (VOD) and high stenosis were diagnosed as VOD. Only light liver tissue VOD patients, difficult to diagnose from clinical symptoms. Severe patients with clinical ascites. Liver histology: 16 of 61 (26%) had VOD. Chemotherapy group of 46 patients in 10 cases (22%) had VOD, including 8 cases of light, 2 cases of heavy; transplantation group 15