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目的探讨阿托伐他汀治疗不稳定型心绞痛临床疗效。方法回顾分析80例患者的临床资料。结果治疗组40例,显效22例,有效17例,无效1例,总有效率98%;对照组40例,显效15例,有效16例,无效9例,总有效率71%;治疗组的显效率及总有效率明显优于对照组,差异有统计学意义(P<0.05)。结论阿托伐他汀有明显的调脂作用和广泛的非调脂作用,可以防止动脉粥样斑块的进展,可恢复血管内皮功能,可抑制斑块中炎症反应及稳定易损斑块,其显著的降低了患者的病死率及致残率,治疗效果确切,值得临床应用。
Objective To investigate the clinical efficacy of atorvastatin in the treatment of unstable angina pectoris. Methods The clinical data of 80 patients were retrospectively analyzed. Results The treatment group of 40 cases, 22 cases markedly effective in 17 cases, 1 case, the total effective rate was 98%; 40 cases in the control group, markedly effective in 15 cases, effective in 16 cases, ineffective in 9 cases, the total effective rate was 71% Significantly effective and total effective rate was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion Atorvastatin has obvious lipid-lowering effects and a wide range of non-lipid-lowering effects, can prevent the progression of atherosclerotic plaque, restore vascular endothelial function, inhibit plaque inflammation and stable vulnerable plaque, which Significantly reduce the mortality and disability of patients, the exact effect, worthy of clinical application.