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目的探讨以上腹痛为主要临床表现的患儿的消化道疾病发病情况及与幽门螺杆菌(Hp)感染的关系。方法借助胃镜检测手段对450例患儿进行临床初步诊断,同时通过病理检测及相关Hp检测,分析消化道疾病与Hp感染的关系。结果疾病检出率为96%;Hp感染率为31.8%,Hp感染前三位疾病分别为消化性溃疡(51.7%)、浅表性胃炎(33.0%)、十二指肠炎(26.7%);Hp感染者病理显示组织损伤明显,两者病变程度呈正比。结论小儿消化道疾病发生率较高,临床缺乏明显的症状与体征,应予高度重视;Hp感染率年龄越大发生率越高;Hp感染是导致消化性溃疡、浅表性胃炎的主要因素之一。
Objective To investigate the incidence of gastrointestinal diseases and its relationship with Helicobacter pylori (Hp) infection in children with the above clinical manifestations of abdominal pain. Methods 450 cases of children with gastroscopy were initially diagnosed clinically, and the relationship between gastrointestinal diseases and Hp infection was analyzed by pathological examination and related Hp detection. Results The positive rate of Hp infection was 31.8%. The first three diseases of Hp infection were peptic ulcer (51.7%), superficial gastritis (33.0%) and duodenitis (26.7%). Hp infection pathology showed obvious tissue damage, both the degree of lesions was proportional. Conclusions The prevalence of gastrointestinal diseases in children is high, and clinical symptoms and signs are lacking. Hp infection rate should be paid more attention to as the age increases. Hp infection is the main factor leading to peptic ulcer and superficial gastritis one.