论文部分内容阅读
[目的]探讨睾丸精原细胞瘤的最佳综合治疗方法。[方法]123例经病理证实的精原细胞瘤在综合治疗后随访。[结果]①5、10年生存率Ⅰ期100%(80/80)、77 5%(62/80) ,Ⅱ期61 1%(11/18)、66 7 %(12/18) ,Ⅲ期20 0%(5/25)、0(0/25)。②Ⅰ期复发率2 5%(2/80) ,无远处转移 ,Ⅱ期复发率16 7%(3/18) ,远处转移率22 2%(4/18) ,Ⅱ期加化疗的复发率10 0%(1/10) ,远处转移率10 0%(1/10) ,Ⅲ期复发率84 0 %(21/25) ,远处转移率72 0%(18/25)。[结论]①综合治疗原则 :Ⅰ期手术加放疗 ,Ⅱ期手术加放疗加化疗 ,Ⅲ期手术加化疗加小野放疗。②腹部有淋巴结转移的不做清扫而要放疗加化疗。③综合治疗时应注意不育问题和正确估价病人承受治疗的能力
[Objective] To explore the best comprehensive treatment of testicular seminoma. [Method] 123 cases of pathologically confirmed seminoma were followed up after comprehensive treatment. [Results] ①The 5-year and 10-year survival rates were 100% (80/80), 77 5% (62/80), 61 1% (11/18), 66 7% 20 0% (5/25), 0 (0/25). ② The recurrence rate was 25% (2/80) in stage Ⅰ, without distant metastasis, the recurrence rate in stage Ⅱ was 16.7% (3/18), the distant metastasis rate was 22.2% (4/18), the relapse in stage Ⅱ plus chemotherapy The rate of metastasis was 100% (1/10) in distant metastasis, 84% (21/25) in stage Ⅲ, and distant metastasis rate was 72.0% (18/25). [Conclusion] ① The principles of comprehensive treatment: Ⅰ surgery plus radiotherapy, Ⅱ surgery plus radiotherapy plus chemotherapy, Ⅲ surgery plus chemotherapy plus radiation therapy. ② abdominal lymph node metastasis and do not do radiotherapy plus chemotherapy. ③ comprehensive treatment should pay attention to the problem of infertility and correct evaluation of the patient’s ability to withstand treatment