论文部分内容阅读
目的了解基层医院外科清洁切口手术围手术期预防用抗菌药物的使用情况,对围手术期预防用抗菌药物的合理性作出评价。方法通过回顾性调查方式,对浙江某县级医院外科住院清洁切口手术患者围手术期预防抗菌药物预防性使用情况进行调查,并进行分析评估。结果共调查该医院外科清洁手术患者1 520例,其中有327例患者接受预防性使用抗菌药物,使用率为21.51%。围手术期预防性使用的主要抗菌药物品种以头孢类占主导,居首位的抗菌药物为头孢呋辛(占82.93%),在预防性使用抗菌药物患者中,有99.69%为单联用药。该医院围手术期用药患者中有12.84%在术后24 h内停药,有61.16%的患者停药是在术后24~48 h;有22.02%的患者用药持续到术后48 h以上。结论该医院清洁切口手术患者围手术期预防性使用抗菌药物方法基本合理,但存在少数给药时间过早或用药持续时间过长等不合理因素,应有针对性地加强管理。
Objective To understand the use of perioperative prophylactic antibiotics in surgical incision and surgical incision in primary hospitals and to evaluate the rationality of perioperative prophylactic antibacterials. Methods By retrospective survey, we investigated the prophylactic use of antimicrobial agents during perioperative period in patients undergoing clean incision surgery in a county hospital in Zhejiang Province and analyzed and evaluated. Results A total of 1 520 cases of surgical clean operation in the hospital were investigated. 327 of them received prophylactic use of antibacterial drugs, with a utilization rate of 21.51%. Cephalosporins dominate the prophylactic use of antibacterials in the perioperative period, with cefuroxime as the first antibiotic (accounting for 82.93%), and single-drug administration of 99.69% of the antibacterials used prophylactically. In the hospital, 12.84% of patients undergoing perioperative treatment discontinued within 24 hours after operation, 61.16% of patients discontinued after 24-48 hours after operation, and 22.02% of patients continued to use more than 48 hours after operation. Conclusions The perioperative prophylactic use of antimicrobial agents in patients undergoing clean incision surgery in this hospital is basically reasonable. However, there are some unreasonable factors such as the premature delivery of medication or the prolonged duration of medication, and should be managed in a targeted manner.