肠上皮内白细胞——一种不寻常的免疫学组份

• 作 者: Ernst PB 姚光弼
• 出 处: 国外医学(消化系疾病分册)
• 发表日期: 1986年04期
• 关键词: 白细胞 粘膜固有层 淋巴样细胞 大分子物质 肠道炎症 肠上皮 细胞介导免疫 肠道 组份 异质性

在肠粘膜上皮细胞之间,有一组异质性的淋巴样细胞,称为上皮内白细胞(intraepitheliat leukocytes,简称:IEL).IEL直接与肠道内大分子物质接触,在一些肠道炎症时增加.IEL与粘膜固有层的淋巴细胞不同,前者具有细胞介导免疫作用,对于防止肠道疾病的发生以及在某些疾病的发病机理中有一定的意义.IEL的形态学和组织化学特点:与呼吸道和泌尿道粘膜的表面一样,在肠道粘膜表面有

Between the intestinal mucosal epithelium, there is a heterogeneous set of lymphoid cells called intraepithelial leukocytes (IEL), which contacts directly with the intestinal macromolecules and increases with some intestinal inflammation. IEL and mucosal lamina propria of different lymphocytes, the former has a cell-mediated immune function, to prevent the occurrence of intestinal diseases and the pathogenesis of certain diseases have a certain significance.IEL’s morphological and histochemical features: with the respiratory tract And urinary tract mucosa surface, the intestinal mucosal surface