论文部分内容阅读
进展期癌症患者体重下降关连到生活质量受损和生存期缩短,其确切机制常不清楚,最近在MAC16鼠结肠腺癌恶病质模型中检出了一种新硫酸化糖蛋白,其分子量为24kDa,该蛋白有调节体重下降的作用;在体重下降的胰腺癌和其他癌症病人尿中也可检测到不同量的该蛋白存在;当给无肿瘤鼠注射
The exact mechanisms underlying the impaired quality of life associated with impaired quality of life and shortened survival in patients with advanced cancer are often unclear. Recently, a new sulfated glycoprotein was identified in the MAC16 rat model of adenocarcinoma of the cachexia with a molecular weight of 24 kDa, The protein has a role in regulating weight loss; different amounts of this protein can also be detected in the urine of patients with decreased body weight of pancreatic cancer and other cancers; when injected into non-neoplastic mice