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目的探讨静脉注射丙种球蛋白(IVIG)对新生儿ABO溶血病的疗效。方法比较ABO溶血病患儿接受IVIG及治疗前后溶血指标的变化。结果两组治疗前各指标无差异(P>0.05);治疗后,总胆红素、网织红细胞数、黄疸消退时间治疗组较对照组显著下降(P<0.05),红细胞数、血红蛋白两组间无差异(P>0.05)。结论 IVIG可阻断溶血,降低胆红素,缩短黄疸时间。
Objective To investigate the effect of intravenous gamma globulin (IVIG) on neonatal ABO hemolytic disease. Methods The changes of hemolysis indexes in children with ABO hemolytic disease after receiving IVIG and before and after treatment were compared. Results There was no significant difference between the two groups before treatment (P> 0.05). After treatment, the total bilirubin, reticulocyte count and jaundice remission time in treatment group were significantly decreased (P <0.05), and the number of erythrocyte and hemoglobin No difference (P> 0.05). Conclusion IVIG can block hemolysis, reduce bilirubin and shorten jaundice time.