论文部分内容阅读
目的探讨糖尿病视网膜病变患者细胞因子E-选择素的水平及其在糖尿病视网膜病变患者诊断及治疗中的意义。方法检测糖尿病无视网膜病变患者(NDR)、糖尿病视网膜病变患者(DR)及健康体检者血清E-选择素含量,对结果进行统计分析。结果NDR组E-选择素水平明显高于正常对照组(P<0.01),DR组E-选择素水平明显高于正常对照组(P<0.01),且明显高于NDR组(P<0.01)。结论E-选择素参与了糖尿病视网膜病变的发病机制,检测E-选择素水平对于糖尿病视网膜病变的早期诊断具有重要意义,对E-选择素的深入研究,有望为糖尿病视网膜病变的治疗开辟新的途径。
Objective To investigate the level of cytokine E-selectin in patients with diabetic retinopathy and its significance in the diagnosis and treatment of diabetic retinopathy. Methods The levels of serum E-selectin in patients with diabetic retinopathy (NDR), diabetic retinopathy (DR) and healthy controls were measured and the results were statistically analyzed. Results The E-selectin level in NDR group was significantly higher than that in normal control group (P <0.01). The E-selectin level in DR group was significantly higher than that in normal control group (P <0.01) . Conclusion E-selectin is involved in the pathogenesis of diabetic retinopathy. Detection of E-selectin level is of great significance for the early diagnosis of diabetic retinopathy. In-depth study of E-selectin may open up new possibilities for the treatment of diabetic retinopathy way.