Skp2和p27kip1与肿瘤关系的研究进展

• 作 者: 李娟娟 闵大六
• 机 构: 安徽省蚌埠医学院附属医院肿瘤内科,
• 出 处: 癌症进展
• 发表日期: 2009年05期
• 关键词: Skp2 p27kip1 肿瘤 泛素

肿瘤的重要特征之一是细胞周期调控机制紊乱,细胞分化受阻,细胞表现为无限制、自主的增殖和分裂。细胞周期主要有两个调定点:G1/S和G2/M期调定点。p27kip1是一种新发

One of the important features of the tumor is disorder of the cell cycle regulation mechanism, blocked cell differentiation, and cells show unlimited and autonomous proliferation and division. The cell cycle has two main set points: G1 / S and G2 / M set point. p27kip1 is a new hair