论文部分内容阅读
目的探讨现场细胞学在超声支气管镜引导下支气管针吸活检的应用价值。方法选取2013年1月至2013年12月间大连医科大学附属大连市中心医院收治的经胸部计算机断层扫描显示肺部病变伴(或不伴)纵隔与肺门淋巴结肿大、肺门和(或)纵隔淋巴结肿大以及纵隔病变患者。随机选取33例患者行现场细胞学联合超声支气管镜引导下经支气管针吸活检。比较分析现场细胞学与组织学的诊断率。结果 33例患者穿刺均成功,穿刺阳性率达到100.0%。其中25例取得阳性组织学病理诊断,8例为非特异性诊断,阳性诊断率为75.8%。现场细胞学涂片可见异型细胞26例,阳性率达到78.8%。现场细胞学疑诊恶性肿瘤阳性率78.8%,后经组织学诊断恶性肿瘤阳性率为66.7%,现场细胞学疑诊恶性肿瘤与组织学诊断恶性肿瘤阳性率的比较,差异无统计学意义(P>0.05)。现场细胞学诊断无假阴性,存在假阳性,假阳性率为15.4%。结论超声支气管镜引导下支气管针吸活检联合现场细胞学不仅可以减少不必要的穿刺,缩短操作时间,而且经济简便。
Objective To explore the value of on-site cytology in bronchial needle aspiration biopsy guided by ultrasound bronchoscopy. Methods From January 2013 to December 2013, the Dalian Central Hospital attached to Dalian Medical University underwent computed tomography (CT) of pulmonary lesions with or without mediastinal and hilar lymph nodes, hilar and / or ) Mediastinal lymph nodes and mediastinal lesions in patients. Thirty-three patients were randomly selected to undergo bronchial needle aspiration biopsy under field cytology combined with ultrasound bronchoscopy. Comparative analysis of on-site cytology and histology diagnostic rate. Results All the 33 cases were successfully punctured, and the positive rate of puncture was 100.0%. Among them, 25 cases were positive histopathological diagnosis, 8 cases non-specific diagnosis, the positive diagnosis rate was 75.8%. On-site cytology smear showed 26 cases of dysplasia, the positive rate of 78.8%. The positive rate of oncology cytology suspicious malignant tumor was 78.8%, and the positive rate of histological diagnosis of malignant tumor was 66.7%. There was no significant difference between on-site cytological suspicious malignant tumor and histological diagnosis of malignant tumor (P > 0.05). On-site cytological diagnosis without false negative, there is a false positive, the false positive rate was 15.4%. Conclusion Ultrasound bronchoscopy guided bronchial needle biopsy combined with on-site cytology can not only reduce unnecessary puncture, shorten the operation time, and the economy is simple.