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目的调查功能性二尖瓣返流患者与正常人相比,瓣叶面积的增加对返流程度的影响。方法共调查78人,分为3组。正常者20人,功能性二尖瓣返流患者28名,无二尖瓣返流的患者30名,观察二尖瓣瓣叶及瓣环面积的改变。结果与心脏正常者相比,患有左室扩大无二尖瓣返流的患者,其瓣叶面积增加,两组之间瓣叶与瓣环面积比值无差异。有功能性二尖瓣返流患者的总瓣叶面积与瓣环面积的比值不足。结论在室壁运动异常和左室扩大无二尖瓣返流的患者中,二尖瓣瓣叶面积的增加是对慢性牵拉和限束的反应。而发生显性二尖瓣返流是由于瓣叶面积与心脏空间结构的改变不适配。
Objective To investigate the effect of increased leaflet area on the degree of regurgitation in patients with functional mitral regurgitation compared with normal subjects. Methods A total of 78 people were surveyed and divided into 3 groups. 20 normal persons, 28 patients with functional mitral regurgitation, 30 patients without mitral regurgitation and observed mitral valve leaflets and valve annulus area changes. Results Compared with healthy subjects, patients with left ventricular enlargement without mitral regurgitation had an increased leaflet area and no difference in the ratio of leaflet to annulus area between the two groups. Patients with functional mitral regurgitation have a low ratio of total valve leaflet area to annulus area. Conclusions In patients with abnormal wall motion and left ventricular enlargement without mitral regurgitation, the increase in mitral valve leaflet area is a response to chronic traction and confinement. The occurrence of dominant mitral regurgitation is due to changes in leaflet area and cardiac space structure does not fit.