脾脏原发性恶性纤维组织细胞瘤1例并文献复习

• 作 者: 冯继峰 刘静
• 机 构: 厦门大学附属东南医院普通外科,
• 出 处: 中国普通外科杂志
• 发表日期: 2011年05期
• 关键词: 脾脏 脾肿瘤 男女发病率 平均生存期 免疫组化检查 平滑肌肉瘤 方法报告 多形性肉瘤 脾切除术 中上极

目的探讨脾脏原发性恶性纤维组织细胞瘤的病因及治疗。方法报告收治的1例脾脏原发性恶性纤维组织细胞瘤,并进行国内外相关文献复习。结果脾脏原发性恶性纤维组织细胞瘤是极其罕见的脾脏恶性肿瘤,国内外文献共有报道26例,加上笔者收治的1例,共27例。好发年龄为40~70岁,男女发病率近似年龄没有统计学差异。结论该病术前诊断困难,确诊依赖病理和免疫组化检查,手术切除是其主要的治疗方式,预后很差,平均生存期(10.2±5.7)个月。

Objective To investigate the etiology and treatment of splenic primary malignant fibrous histiocytoma. Methods One case of primary malignant fibrous histiocytoma of spleen was treated and reported in the literature review at home and abroad. Results Spleen primary malignant fibrous histiocytoma is an extremely rare malignant tumor of the spleen. There are 26 cases reported in domestic and foreign literatures, and 1 case was treated by the author, a total of 27 cases. Good hair age of 40 to 70 years old, male and female incidence of similar age did not reach statistical significance. Conclusions The preoperative diagnosis is difficult. The diagnosis depends on pathology and immunohistochemistry. Surgical resection is the main treatment method. The prognosis is poor with an average survival of (10.2 ± 5.7) months.