One-step synthesis of inherently chiral p-tert-butylcalix[4]azacrown

• 出 处: Chinese Chemical Letters
• 发表日期: 2009年06期
• 关键词: chiral arene calix substitution synthesize substituent prepare bridging hydroxye

A one-step procedure is developed to synthesize inherently chiral p-tert-butylcalix[4]azacrown 1 through etherification between p-tert-butylcalix[4]arene and compound 3,which can be amplified to efficiently prepare more inherently chiral calix[4]arenes in ABHH substitution pattern.

A one-step procedure is developed to synthesize inherently chiral p-tert-butylcalix [4] azacrown 1 through etherification between p-tert-butylcalix [4] arene and compound 3, which can be amplified to efficiently prepare more inherently chiral calix [4] ] arenes in ABHH substitution pattern.