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目的:探究于妊娠期甲状腺功能亢进孕妇临床治疗中联合应用左甲状腺素片与丙基硫氧嘧啶治疗的效果,以及对其妊娠结局的影响分析.方法:选取我院2020年1月-2021年6月收治的妊娠期甲状腺功能亢进孕妇90例,将其随机分为例数相等的对照组与研究组,其中前组单用丙基硫氧嘧啶治疗,后组则予以左甲状腺素片联合丙基硫氧嘧啶治疗,对比两组孕妇治疗效果、血清甲状腺素水平以及不良妊娠结局.结果:研究组孕妇治疗效果明显优于对照组,P＜0.05;治疗后研究组孕妇游离甲状腺素(FT4)、游离三碘甲状腺原氨酸(FT3)以及促甲状腺激素“,”Objective: To investigate the effect of levthyroxine and pylthiil in clinical treatment of hyperthyroidism women during pregnancy and analyze the effect on pregnancy outcome. Methods : 90 hyperthyroidism pregnant women with pregnancy treated from January 2020 to June 2021 were randomly divided into equal control groups and researchers, treated with pyril alone, then left thyroxyl, comparing the treatment effect, serum thyroxine levels and adverse pregnancy outcome. Results : Pregnant women were significantly better than the control group, P ＜ 0. 05 , free thyroxine ( FT4) , free triothyrogenine ( FT3 ) and TSH) , P ＜ 0. 05 ; the incidence of adverse pregnancy outcomes were lower than the control group, P ＜ 0. 05. Conclusion : The application of left thyroxine in pregnant women, which can improve serum thyroxine and reduce the occurrence of adverse pregnancy outcome.