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目的研究探讨白三烯受体拮抗剂在小儿支气管哮喘患者中的应用及其疗效。方法本院哮喘专科门诊支气管哮喘轻、中度患儿40例,按随机法分为实验组和对照组,每组20例。实验组给予白三烯受体拮抗剂,对照组给予糖皮质激素。评价各组临床症状缓解时间、症状消失时间、有效率、不良反应等,并进行统计学分析。结果两组临床症状缓解时间、症状消失时间、有效率、不良反应等明显不同(P<0.05)。结论在支气管哮喘患儿治疗中,白三烯受体拮抗剂治疗效果显著,且无明显不良反应,值得推广应用。
Objective To investigate the use of leukotriene receptor antagonists in children with bronchial asthma and its efficacy. Methods A total of 40 mild and moderate children with bronchial asthma were randomly divided into experimental group and control group with 20 cases in each group. Experimental group leukotriene receptor antagonist, the control group given glucocorticoid. Evaluation of clinical symptoms in each group to alleviate the time, symptoms disappear time, efficiency, adverse reactions, and statistical analysis. Results The time of symptom relief, symptom disappearance time, effective rate and adverse reaction were significantly different between the two groups (P <0.05). Conclusion The treatment of patients with bronchial asthma leukotriene receptor antagonist significant effect, and no significant adverse reactions, it is worth promoting the application.