Role of axon resealing in retrograde neuronal death and regeneration after spinal cord injury

• 作 者: William Rodemer Michael E.Selz
• 机 构: ShrinersHospitalPediatricResearchCenter（CenterforNeuralRepairandRehabilitation）,DepartmentofNeurolog
• 出 处: 中国神经再生研究:英文版
• 发表日期: 2019年3期
• 关键词: AXON resealing REGENERATION RETROGRADE NEURONAL death spinal cord injury sea LAM
• 基金项目: grants R01-NS092876(NIH,to MES),SHC-85400(Shriners Research Foundation,to MES),SHC-85220(Shriners Research Foundation,to MES).

Spinal cord injury leads to persistent behavioral deficits because mammalian central nervous system axons fail to regenerate.A neuron's response to axon injury results from a complex interplay of neuron-intrinsic and environmental factors.The contribu