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为验证血液降解释放的铁离子是否为玻璃体液化的主要因素,将0.7微麾尔氯化亚铁溶液注入兔眼玻璃体,结果在2周内使玻璃体完全液化,玻璃体胶原纤维呈颗粒状或絮状沉淀,而0.1微麾尔亚铁溶液没有引起明显的玻璃体改变,但造成了后极部视网膜外核层破坏。巨噬细胞浸润到玻璃体视网膜界面时,可出现局部玻璃体后脱离。本实验证实使兔眼玻璃体液化的最低铁离子量为16.8至36.2微克或相当于0.3至0.7毫麾尔浓度。
In order to verify whether the iron ions released by blood degradation are the main factors of vitreous liquefaction, a 0.7 micro-ferrocene ferrous chloride solution was injected into the vitreous of rabbits and the vitreous was completely liquefied within 2 weeks. The vitreous collagen fibers were granular or flocculent Precipitation, while 0.1 micro-ferrous ferrous solution did not cause significant changes in the vitreous, but caused posterior pole retinal outer nuclear layer damage. Macrophage infiltration into the vitreoretinal interface, there may be local vitreous detachment. This experiment demonstrated that the minimum amount of iron ions that liquefy the vitreous of the rabbit eye is 16.8 to 36.2 micrograms or equivalent to 0.3 to 0.7 milliliter concentration.