Degradation Kinetics of Scutellarin in Water Extract of HERBA SCUTELLARIAE BARBATAE

• 作 者: LI Yi-sheng GAO Han LIU Jiang-qi GENG Xiao-rui QIU Shu-qi SU Zi-ren
• 机 构: Shenzhen ENT Institute,ENT Hospital of Longgang Central Hospital,Guangzhou University of Chinese Med
• 出 处: Medicinal Plant
• 发表日期: 2012年12期
• 关键词: kinetics immersed extracting fastest immersion unchanged enzymatic methanol batc

[Objective] To study the change of scutellarin in HERBA SCUTELLARIAE BARBATAE under different immersing conditions. [Method] HPLC was adopted to detect the content of scutellarin in water extract of HERBA SCUTELLARIAE BARBATAE immersed at different temperatures and times. The scutellarin content and soaking time were selected as variants of dynamic equation and the kinetics parameters were calculated. [Result] Under the immersing conditions of temperature from 20 to 60 ℃,the change of scutellarin content tended to show degradation characteristic in water extract of HERBA SCUTELLARIAE BARBATAE, and degradation rate was the fastest between 30 and 40 ℃. While the scutellarin content in water extract remained unchanged at the immersing temperature above 70 ℃ and it had a higher extraction rate. [Conclusion] Scutellarin of HERBA SCUTELLARIAE BARBATAE exists enzymatic degradation reaction in the process of immersion. It is better to put HERBA SCUTELLARIAE BARBATAE at the temperature above 70 ℃ when water extracting, in which way can effectively increase the extraction rate of scutellarin.

[Objective] To study the change of scutellarin in HERBA SCUTELLARIAE BARBATAE under different immersing conditions. [Method] HPLC was been detected to the content of scutellarin in water extract of HERBA SCUTELLARIAE BARBATAE immersed at different temperatures and times. The scutellarin content and soaking time were selected as variants of dynamic equation and the kinetics parameters were calculated. [Result] Under the immersing conditions of temperature from 20 to 60 ° C., the change of scutellarin content tended to show degradation characteristic in water extract of HERBA SCUTELLARIAE BARBATAE, and degradation rate was the fastest between 30 and 40 ° C. While the scutellarin content in water extract remained unchanged at the immersing temperature above 70 ° C. and it had a higher extraction rate. [Conclusion] Scutellarin of HERBA SCUTELLARIAE BARBATAE exists enzymatic degradation reaction in the process of immersion It is better to put HERBA SCUTELLARIAE BARBATAE at the temperature ab ove 70 ℃ when water extracting, in which way can effectively increase the extraction rate of scutellarin.