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Carboxymethylpachyman(Ⅰ)was formed by carboxymethylation ofβ-pachyman.The antitumour activity of carboxymethylpachyman(Ⅰ)against S<sub>180</sub>、EAC、MA、U<sub>14</sub>was measured.The structure of carboxymethylpachyman(Ⅰ)was proved