~(99)Tc~m-MDP骨显像对乳腺癌骨转移特征的评价分析

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目的:探讨原发性乳腺癌患者骨骼转移病灶的影像特征。方法:对212例病理确诊的乳腺癌患者行全身骨骼显像,分析各骨骼骨转移率、病灶构成及病灶形态特征。结果:患者骨转移率41.5%(88/212),中轴骨骨转移率38.7%(82/212),四肢骨20.3%(43/212),中轴躯干骨38.7%(82/212),四肢带骨18.4%(39/212),肋骨、胸椎、腰椎、髂骨、胸骨骨转移率较高。身体左右两侧病灶数目差异无统计学意义,χ2=0.356,P=0.551。骨转移病灶形态:点状72.9%(495/679),团状14.7%(100/679),条状7.5%(51/679),片状4.9%(33/679)。浓聚病灶98.7%(760/770),混合性病灶0.5%(4/770),稀疏病灶0.8%(6/770)。结论:乳腺癌易发生骨转移,骨转移好发于中轴躯干骨和四肢带骨。早发病灶分布无明确规律,晚期骨转移病灶随机性广泛分布,并且常呈多发性多形态病灶并存的特征。 Objective: To investigate the imaging features of bone metastases in patients with primary breast cancer. Methods: Totally 212 patients with pathologically diagnosed breast cancer underwent whole body scintigraphy. The skeletal bone metastases, lesions and lesions were analyzed. Results: The rate of bone metastasis was 41.5% (88/212), 38.7% (82/212) in the central axis, 20.3% (43/212) in the extremities and 38.7% (82/212) in the medial axis trunk, The limbs with bone 18.4% (39/212), rib, thoracic, lumbar, iliac, sternal bone metastasis rate higher. No significant difference in the number of lesions on the left and right sides of the body, χ2 = 0.356, P = 0.551. The morphological changes of the bone metastases were as follows: 72.9% (495/679) points, 14.7% (100/679) pellets, 7.5% (51/679) strips and 4.9% (33/679) pellets. Concentrated lesions 98.7% (760/770), mixed lesions 0.5% (4/770), sparse lesions 0.8% (6/770). Conclusion: Breast cancer prone to bone metastasis, bone metastases occur in the trunk torso shaft and limb with bone. Early distribution of lesions no clear law, the late random distribution of bone metastases widely distributed, and often multiple poly morphological lesions coexist characteristics.
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