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52例原发性震颤麻痹用左旋多巴或美多巴治疗后平均83个月出现药效减退,并能诱发“开～关”现象和多动症等,此时联合或单独应用溴隐亭治疗能取得良好效果,有效37例(71.5％)。本组平均治疗剂量8.8mg/日。47例兼用美多巴者有21例使原美多巴用量减少34.6％。本品对美多巴诱发的“开～关”现象与多动症也有效。常见副作用有恶心、呕吐、食欲减退等,有1例出现心脏症状且ECG示心肌损害,3例有明显的精神症状。
52 cases of primary paralysis paralysis with levodopa or methyclopa treatment of an average of 83 months after the onset of efficacy diminished and can induce the “open ~ off” phenomenon and ADHD, etc., at this time combined or single application of bromocriptine can Obtained good results, effective in 37 cases (71.5%). The average therapeutic dose of 8.8mg / day. Of the 47 patients with combined use of metoprolol, 21 had a 34.6% reduction in the use of prochodopsin. This product induced by the US Toba “open ~ off” phenomenon and ADHD also effective. Common side effects are nausea, vomiting, loss of appetite, etc., 1 case of cardiac symptoms and ECG showed myocardial damage, 3 patients had significant mental symptoms.