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应用ＲＴ－ＰＣＲ方法分别对肝癌高发家庭及非癌家庭成员各５５人血清中的ＨＣＶＲＮＡ进行检测。结果表明，肝癌高发家庭成员中ＨＣＶＲＮＡ阳性率为１０．９％（６／５５），而非癌家庭成员阳性率为２１．８％（１２／５５），经统计分析两组阳性率无显著性差异（Ｐ＞０．０５）。同时，两组对象均无ＨＣＶＲＮＡ家庭聚集现象。提示：ＨＣＶ的感染和复制与广西ＨＣＣ家庭聚集性无明显关系，但不能除外两组ＨＣＶ基因亚型的差异。
The HCV RNA in serum of 55 individuals with HCC and non-cancer family members were detected by RT-PCR. The results showed that the positive rate of HCVRNA was 10.9% (6/55) in high-risk HCC family members, while it was 21.8% (12/55) in non-cancer family members. There was no significant difference between the two groups Difference (P> 0.05). At the same time, there was no aggregation of HCV RNA in both groups. Tip: HCV infection and replication and Guangxi HCC family aggregation no significant relationship, but can not be excluded except for differences in HCV genotypes between the two groups.