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目的:探讨早发型重度子痫前期终止妊娠时机对母婴预后结局的作用,为临床实践提供指导。方法:从2007年1月至2010年12月期间在我院妇产科分娩并为重度子痫前期患者中随机选取135例作为研究对象。按终止妊娠时间分为两组,A组<32周、32周≤B组≤34周。对两组均终止妊娠,比较两组间血压状况、尿蛋白、血小板、凝血、眼底状况及胎儿监护。结果:A组的胎盘早剥、子痫和肾功能损害的发生率略高于B组,然而差异均无统计学意义(P>0.05)。A组的新生儿窒息率,新生儿呼吸窘迫综合征发生率,围产儿死亡率等3个指标均明显高于B组,且卡方检验显示,两组比较差异有显著性(P<0.05)。结论:对于终止妊娠的时间、方式应根据患者的状况进行综合考虑。无论选择何时终止妊娠或治疗,都应该综合考虑母婴两方面的状况,密切进行监护,尽量获得良好的结局。
Objective: To explore the effect of premature termination of preeclampsia on the outcomes of pregnancy and termination of pregnancy, and provide guidance for clinical practice. Methods: From January 2007 to December 2010 in our hospital obstetrics and gynecology during delivery and 135 cases of severe preeclampsia were randomly selected as the research object. According to the termination of pregnancy time is divided into two groups, A group <32 weeks, 32 weeks ≤ B group ≤ 34 weeks. Pregnancy was terminated in both groups and blood pressure, urine protein, platelets, coagulation, fundus status and fetal monitoring were compared between the two groups. Results: The incidence of placental abruption, eclampsia and renal dysfunction in group A was slightly higher than that in group B, however, the differences were not statistically significant (P> 0.05). A group of neonatal asphyxia, neonatal respiratory distress syndrome incidence, perinatal mortality and other three indicators were significantly higher than the B group, and the chi-square test showed that the difference between the two groups was significant (P <0.05) . Conclusions: The timing of termination of pregnancy should be based on the patient’s condition. Whenever you choose to terminate your pregnancy or treatment, you should take both mother and baby into account and monitor your childcare closely to get a good outcome.