论文部分内容阅读
一些证据表明松弛素在妊娠中有重要作用。有关妊娠大鼠和豚鼠中的作用已有报道。在人的妊娠中其作用不很清楚。合成的人松弛素(hRLX-2)也有效。为此研究了合成的 hRLX-2对离体大鼠和人子宫肌及足月妊娠子宫胎盘动脉的作用。实验用成熟未交配过的 Wistar 大鼠(n=8)的离体子宫角,制成直径1～2 mm 长10mm 的组织条。足月妊娠剖宫产妇女的子宫峡部、底部子宫肌的活组织(n=6) ,及正常足月分娩的胎盘分离的正常绒毛叶。放入冷 Krebs 液中,后制成大小同大
There is some evidence that relaxin plays an important role in pregnancy. The effects on pregnant rats and guinea pigs have been reported. Its role in human pregnancy is not clear. Synthetic human relaxin (hRLX-2) is also effective. For this purpose, the effect of synthetic hRLX-2 on isolated rat and human uterine muscles and uterine placental arteries in full-term pregnancy was studied. Experiments were performed on isolated uterine horns of mature unpaired Wistar rats (n = 8) to create a tissue strip of 1 mm in diameter and 10 mm in length. The uterine isthmus of the cesarean section of full-term pregnancy, the living tissue of the bottom uterine muscle (n = 6), and the normal villous leaf isolated from the placenta of normal full-term delivery. Into the cold Krebs liquid, made of the same size