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白喉的发病年龄向大年龄组推移的现象国内外均有报导。1974~1975年我省局部地区白喉流行,据三个县的资料统计,8~15岁儿童及成人发病占80%以上,其原因与免疫力不足有关。如何提高这部分人群的免疫力以控制流行是急待解决的问题。以往认为这些对象接种白喉类毒素必须先做锡克氏试验,阳性者仍需做莫尼氏试验,阴性者方可接种,以免发生加重反应或超敏反应。而上述两试验工作量大,在农村广泛开展的困难较大。能否免做试验呢?我们于1976年通过试点,对大年龄儿童进行精制吸附白喉类毒素(以下简称“吸精白类”)
The incidence of diphtheria age group to the phenomenon of large age groups have been reported at home and abroad. In the period from 1974 to 1975, diphtheria was endemic in some areas of our province. According to the statistics of three counties, the incidence of children and adults aged 8-15 years accounted for more than 80%. The reason was related to the deficiency of immunity. How to improve the immunity of this part of the population to control the epidemic is an urgent issue to be solved. In the past that these subjects vaccination diphtheria toxoid must do Sick’s test, the positive still need to do Monet test, negative persons can be vaccinated, so as to avoid aggravating reactions or hypersensitivity reactions. However, the workload of the above two experiments is large and the difficulties that are widely carried out in rural areas are large. Can we exempt from experiment? We passed the pilot in 1976 to carry out the purification and adsorption of diphtheria toxoid (hereinafter referred to as “white-absorbing type”) to children of large ages