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目的分析降糖药的使用情况和变化趋势,了解医生使用口服降糖药处方的习惯,以促进临床更合理使用药物。方法用药频度(DDDs)和药物利用指数(DUI)作为分析判断药物利用情况指标,并对降糖药物间联合使用情况进行分析。结果2005年和2006年降糖药费用增长率为-25.60%和45.86%。主要口服降糖药有10种;除瑞格列奈、格列本脲和格列美脲的DUI略大于1外,其他降糖药的DUI≤1;2004年至2006年降糖药间联用处方分别有9 854张、9 510张和9 756张。结论我院降糖药使用基本合理,无滥用现象,口服降糖药利用情况与其自身的特点密切相关。
Objective To analyze the usage and trends of hypoglycemic agents and to understand the habit of using oral hypoglycemic agents by doctors in order to promote more rational use of drugs in clinical practice. Methods The frequency of drug use (DDDs) and drug use index (DUI) were used as indexes to determine the drug utilization status, and the combination of hypoglycemic agents was analyzed. Results The cost of hypoglycemic drugs in 2005 and 2006 increased by -25.60% and 45.86% respectively. The main oral hypoglycemic agents are 10; except DRE of repaglinide, glibenclamide and glimepiride is slightly larger than 1, DUI of other hypoglycemic agents is less than 1; between 2004 and 2006, There were 9 854, 9 510 and 9 756 prescriptions respectively. Conclusion The use of hypoglycemic agents in our hospital is basically reasonable and no abuse. The utilization of oral hypoglycemic agents is closely related to its own characteristics.