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本文报道用抗乙肝免疫核糖核酸(IRNA)加乙肝疫苗治疗慢性乙型肝炎及慢性乙肝病毒携带者(20例)有较好抗病毒作用,特别是对HBeAg转阴效果最佳,阴转率为85%,与用转移因子(TF)对照组相比明显高于后者(P<0.01);并有促进HBsAb生成的远期效果。
In this paper, IRNA and hepatitis B vaccine treatment of chronic hepatitis B and chronic hepatitis B virus carriers (20 cases) have better antiviral effect, especially for HBeAg negative best negative conversion rate was 85%, which was significantly higher than that of the control group (P <0.01) and the long-term effect of promoting HBsAb production.