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羊膜穿刺术用于检测胎儿染色体异常始于70年代初。本文回顾分析美国七个最大州之一的俄亥俄州应用羊膜穿刺术头12年(1972～1984年)的情况。本文资料包括1972.1.1～1984.7.1在俄亥俄州居住并因细胞遗传分析而行羊膜穿刺术的全部妇女的情况。资料分析表明:该州1972年行羊膜穿刺术共21次,1983年增至全年2,400次,12年间年平均增长率为43.1%。1978.7.1～1984.7.1,共行羊膜穿刺术10,481例,近71%是因孕妇年龄≥35岁;15%是
Amniocentesis for the detection of fetal chromosomal abnormalities began in the early 1970s. This article reviews the first 12 years (1972-1984) of using amniocentesis in Ohio, one of the seven largest states in the United States. This document includes all women who lived in Ohio from January 1972 to January 1984 and underwent amniocentesis for cytogenetic analysis. Data analysis shows that in 1972, the state had performed amniocentesis for 21 times in 1983 and increased to 2,400 times in the whole year, with an average annual growth rate of 43.1% in 12 years. 1978.7.1 ~ 1984.7.1, co-line amniocentesis 10,481 cases, nearly 71% because of pregnant women aged 35 years or older; 15%