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探讨体外射频热疗联合α受体阻滞剂治疗前列腺增生症(BPH)的安全性及近、远期疗效。方法采用随机对照方法。将90例有症状的BPH患者,随机分为3组,各30例。分别接受热疗(Ⅰ组)、受体阻滞剂(Ⅱ组)和热疗联合受体阻滞剂(Ⅲ组)等治疗。在18个月的随访期中,分期观察、比较各组的主、客观疗效。结果Ⅲ组近期(6个月以内)的主、客观疗效显著优与Ⅰ、Ⅱ组,远期疗效(6个月以上)优与Ⅰ组,但与Ⅱ组相当。结论体外射频热疗联合α受体阻滞剂是一种安全、简单和完全非侵入性的方法,对症状严重而无法手术的BPH患者,尤其适用。
To investigate the safety and short-term and long-term efficacy of extracorporeal radiofrequency thermotherapy combined with αreceptor blocker in the treatment of benign prostatic hyperplasia (BPH). Methods Randomized controlled methods. 90 patients with symptomatic BPH were randomly divided into three groups, 30 cases each. They were treated with hyperthermia (group Ⅰ), receptor blockers (group Ⅱ) and hyperthermia combined with receptor blockers (group Ⅲ) respectively. During the 18-month follow-up period, the patients were observed by staging and the main and objective effects of each group were compared. Results The main and objective curative effects of group Ⅲ were significantly superior to those of group Ⅰ and Ⅱ in the short term (within 6 months), and group Ⅰ and group Ⅰ with long-term efficacy (more than 6 months), but comparable with group Ⅱ. Conclusions Extracorporeal radiofrequency thermotherapy combined with alpha-blocker is a safe, simple and completely noninvasive method and is especially suitable for BPH patients with severe symptoms and inoperable.