TLR4 upregulates CBS expression through NF-κB activationin a rat model of irritable bowel syndrome w

• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2015年28期
• 关键词: IRRITABLE bowel syndrome DORSAL rootganglion VISCERAL HYPERSENSITIVITY Hydrogen
• 基金项目: Supported by National Natural Science Foundation of China,No.81230024,No.81471137(to GYX)and No.31400947(to HHZ),Priority Academic Program Development of Jiangsu Higher Education Institutions

AIM To investigate the roles of toll-like receptor 4（TLR4） and nuclear factor （NF）-κB on cystathionine βsynthetase （CBS） expression and visceral hypersensitivityin rats.METHODS： This study used 1-7-wk-old male Sprague-Dawley rats. Western blot analysis wa