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目的 :观察用带结膜瓣的自体角膜缘 (干细胞 )移植术治疗翼状胬肉的疗效 ,探索其显微手术技术的改进及其安全性。方法 :选择进行期翼状胬肉 2 5例 2 6眼、复发性翼状胬肉 5例 5眼 ,采取显微手术取同侧眼下方角膜缘带结膜瓣的角膜缘游离移植片进行移植。缝合时强调移植片移植床上角膜缘各自准确对位吻合。术后对角膜上皮化及植片生长情况严密追踪观察。结果 :经过平均 1年 9个月观察无 1例胬肉复发 ,角膜上皮稳定、泪膜正常、供区角膜创面正常愈合。结论 :同侧眼带结膜瓣自体角膜缘 (干细胞 )移植治疗翼状胬肉为较佳的方法。术后供区角膜创面能正常愈合 ,角膜上皮状态稳定 ,泪膜正常 ,未发现术眼出现干细胞代偿功能不全的有关表现及无 1例胬肉复发。此术式是一种高效安全的治疗胬肉的方法。
Objective: To observe the curative effect of autologous limbal stem cell transplantation with conjunctival flap in the treatment of pterygium, and to explore the improvement and safety of its microsurgical technique. Methods: Twenty-five cases (26 eyes) of pterygium and 5 cases (5 cases) of recurrent pterygium were selected for microsurgery. The corneal limbal free graft of the conjunctival flap of the lower limbus at the same side of the eye was used for transplantation. Sutures emphasize the corneal margin on the transplanted bed accurately aligned with each other. Postoperative corneal epithelialization and growth of implants closely tracked. Results: After an average of 1 year and 9 months, there was no recurrence of pterygium. The corneal epithelium was stable and the tear film was normal. The corneal wound healing was normal. Conclusion: Autologous corneal limbal stem cell transplantation for the treatment of pterygium with ipsilateral ocular conjunctival flap is the best method. The corneal wound surface could healed normally, the corneal epithelium was stable and the tear film was normal. There was no recurrence of pterygium with compensatory dysfunction of stem cells. This technique is a safe and effective method of treating pterygium.