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目的:观察骨化三醇联合阿仑膦酸钠及甲巯咪唑治疗甲亢性骨质疏松的临床疗效。方法:选取60例甲亢性骨质疏松患者作为研究对象,按治疗方法不同分为对照组和观察组各30例。观察组患者采用甲巯咪唑+骨化三醇+阿仑膦酸钠进行治疗,对照组患者采用甲巯咪唑和阿仑膦酸钠治疗。观察患者临床疗效及治疗前后的相关临床指标情况。结果:观察组临床治疗总有效率为93.33%,明显优于对照组的70.00%,差异具有统计学意义(P<0.05);治疗后观察组患者的疼痛指数、BMD、BLAP和BGP明显优于对照组,差异具有统计学意义(P<0.05)。结论:骨化三醇联合阿仑膦酸钠及甲巯咪唑治疗甲亢性骨质疏松患者临床疗效较好,值得临床推广应用。
Objective: To observe the clinical efficacy of calcitriol combined with alendronate and methimazole in treatment of hyperthyroidism osteoporosis. Methods: 60 patients with hyperthyroidism osteoporosis were selected as the research object, divided into control group and observation group according to different treatment methods. Patients in the observation group were treated with methimazole + calcitriol + alendronate, and patients in the control group were treated with methimazole and alendronate. To observe the clinical efficacy of patients before and after treatment and related clinical indicators. Results: The total effective rate of clinical observation in observation group was 93.33%, which was significantly better than that in control group (70.00%), the difference was statistically significant (P <0.05); the pain index, BMD, BLAP and BGP in observation group were significantly better than those in observation group Control group, the difference was statistically significant (P <0.05). Conclusion: Calcitriol combined with alendronate and methimazole for hyperthyroidism osteoporosis patients with good clinical efficacy, it is worth promoting the clinical application.