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目的:缬沙坦+胺碘酮治疗孤立性心房颤动的疗效。方法:选择40例孤立性房颤患者,随机分为治疗组和对照组各20例。两组均予胺碘酮口服,治疗组加缬沙坦口服,以12导心电图和HOTEL行疗效评定。结果:两组药物转复率无统计学差异(P>0.05),治疗组窦律维持率优于对照组(P<0.05),两组不良反应无统计学差异(P>0.05)。结论:缬沙坦+胺碘酮治疗孤立性房颤有效,维持窦律优于单用胺碘酮。
Objective: Valsartan + amiodarone in the treatment of isolated atrial fibrillation. Methods: Forty isolated patients with isolated atrial fibrillation were randomly divided into treatment group (n = 20) and control group (n = 20). Both groups were given amiodarone orally, the treatment group plus valsartan oral, with 12-lead ECG and HOTEL line curative effect assessment. Results: There was no significant difference in the rate of drug conversion between the two groups (P> 0.05). The maintenance rate of sinus rhythm in the treatment group was better than that of the control group (P <0.05). There was no significant difference between the two groups (P> 0.05). Conclusion: Valsartan + amiodarone is effective in treatment of isolated atrial fibrillation, and the maintenance of sinus rhythm is superior to amiodarone alone.