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目的:应用定量组织速度成像技术评价原发性高血压(EH)患者心脏的左室局部心肌功能。方法:将40例EH患者按左室心肌质量指数分为:左室肥厚(LVH)组(14例)和非左室肥厚(NLVH)组(26例),另30例正常同龄人为正常对照组。获得心尖四腔、两腔及心尖左室长轴切面各室壁的心肌组织速度曲线,测定收缩期、舒张早期、房缩期的平均峰值速度(VS、VE、VA)及VE/VA。结果:VS:NLVH组及LVH组各室壁均与对照组无显著性差异;VE:NLVH组后间隔、左室后壁、前间隔、下壁较对照组显著降低(P<0.05),LVH组除左室侧壁外其余室壁较对照组显著降低(P<0.05)。VA:NLVH组后间隔与对照组有显著性差异,LVH组各室壁均与对照组有显著性差异(P<0.05)。VE/VA:NLVH组除左室侧壁外其余室壁均较对照组显著降低(P<0.05)。LVH组各室壁均与对照组有显著性差异(P<0.05)。结论:定量组织速度成像能够客观、准确的评价EH患者的局部心肌功能。
Objective: To evaluate left ventricular regional myocardial function in patients with essential hypertension (EH) by quantitative tissue velocity imaging. Methods: 40 cases of EH were divided into two groups according to left ventricular mass index: left ventricular hypertrophy group (n = 14) and non-left ventricular hypertrophy group (n = 26), and the other 30 normal controls were normal control group . The myocardial tissue velocity curves were obtained from the apical four chambers, the two chambers and the apical left ventricular long axis. The mean peak velocity (VS, VE, VA) and VE / VA of systolic, early diastolic and systolic phases were measured. Results: There was no significant difference between VSV NLVH group and LVH group in comparison with the control group. VE: NLVH group was significantly lower than the control group (P <0.05), posterior septum, anterior septum, In addition to the left ventricular wall, the other ventricular wall was significantly lower than the control group (P <0.05). There was a significant difference between the VA: NLVH group and the control group, and the LVH group had significant difference (P <0.05) with the control group. VE / VA: NLVH group in addition to the left ventricular wall outside the other walls were significantly lower than the control group (P <0.05). LVH group of each wall were significantly different from the control group (P <0.05). Conclusion: Quantitative tissue velocity imaging can objectively and accurately evaluate the local myocardial function in patients with EH.