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Purpose:To describe the clinical features of post-streptoc-occal uveitis(PSU)and examine management strategies in the treatment of this under-recognized condition.Methods:Patients were identified from the world literature using the Pubmed search engine.We examined two new cases of post-streptococcal intermediate uveitis.The epidemiology,immune mechanisms,clinical features,investigations,treatments and visual outcomes were examined and recorded.Results:We reviewed 11 patients including our own two cases.There was a statistically significant seasonal difference in antistreptolysin-O titres(ASOT),and age-related ASOT was identified.Of the 11 patients,eight(72.7%)had anterior uveitis,two(18.2%)had intermediate uveitis and one(9.1%)had panuveitis.Their ages ranged from 5 to 56 years(mean 17 years).The majority of cases had significantly elevated ASOT;most patients were treated with topical steroids and oral antibiotics and four cases underwent adenotonsillectomy.The visual prognosis was good in most cases.Conclusions:Uveitis may be the sole presenting clinical feature,or it may occur in combination with other features of post-streptococcal infection.Ophthalmologists should be aware of the clinical features of PSU and maintain a high level of suspicion,particularly in childhood uveitis.
Purpose: To describe the clinical features of post-streptoc-occal uveitis (PSU) and examine management strategies in the treatment of this under-recognized condition. Methods: Patients were identified from the world literature using the Pubmed search engine. We examined two new cases of post-streptococcal intermediate uveitis. epidemiology, immune mechanisms, clinical features, investigations, treatments and visual outcomes were examined and recorded. Results: We reviewed 11 patients including our own two cases. were was a significant seasonal difference in antistreptolysin- Ortres (ASOT), and age-related ASOT was identified. Of the 11 patients, eight (72.7%) had anterior uveitis, two (18.2%) had intermediate uveitis and one (9.1%) had panuveitis. to 56 years (mean 17 years). the majority of cases had significantly elevated ASOT; most patients were treated with topical steroids and oral antibiotics and four cases underwent adenotonsillectomy.The visual prognosis was goo d in most cases. Conclusions: Uveitis may be the sole presenting clinical feature, or or may occur in combination with other features of post-streptococcal infection. Ophthalmologists should be aware of the clinical features of PSU and maintain a high level of suspicion, particularly in childhood uveitis