论文部分内容阅读
目的：观察视网膜色素变性（ｒｅｔｉｎｉｔｉｓｐｉｇｍｅｎｔｏｓａ，ＲＰ）患者视觉电生理与心理物理学的改变，探讨其视网膜的病理生理变化。方法：对５８例（１１３眼）作暗适应红光和蓝光视网膜电图（ｅｌｅｃ－ｔｒｏｒｅｔｉｎｏｇｒａｍ，ＥＲＧ），明适应白光ＥＲＧ，黄斑中心色光阈值（ｃｏｌｏｒｌｉｇｈｔｔｈｒｅｓｈｏｌｄ，ＣＬＴ）和Ｄ－１５色相配列检测并进行分析。结果：１１３只眼暗适应红光ＥＲＧ均出现异常，１１１只眼（９８．２３％）暗适应蓝光及暗适应白光ＥＲＧ异常，８８只眼（７７．８７％）黄斑中心ＣＬＴ异常；作Ｄ－１５色相配列检查的５５只眼中３０只眼（５４．５４％）有不同程度色觉异常。暗适应红光ＥＲＧｂ波波幅与病程、视力及视野间均无明显的相关性。结论：ＲＰ不仅存在视网膜杆体功能异常，锥体功能亦有紊乱。暗适应红光ＥＲＧ是较全面反映ＲＰ患者视网膜功能的简便、敏感的客观检测方法。
Objective: To observe the changes of visual electrophysiology and psychophysics in patients with retinitis pigmentosa (RP) and to explore the pathophysiological changes of the retina. Methods: Fifty-eight subjects (113 eyes) underwent dark-adapted red and blue electroretinogram (ERG), bright-adapted white light ERG, color center luminosity threshold (CLT) and D- analysis. RESULTS: All of the 113 eyes were dark-adapted to red ERG, abnormalities were found in 111 eyes (98.23%) with dark-adapted and dark-adapted ERG abnormalities, and 88 eyes (77.87%) with abnormal CLT. Thirty eyes (54.54%) in 55 eyes of 15 color matching examinations had different degrees of color vision abnormalities. Dark adaptation ERGb amplitude and duration of disease, visual acuity and visual field were no significant correlation between. Conclusion: RP not only has abnormal retinal rod function, pyramidal function is also disorder. Dark-adapted red ERG is a simple, sensitive and objective method to detect the retinal function in patients with RP.