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目的探究~(131)碘(~(131)I)治疗甲状腺功能亢进症(甲亢)患者的后期随访效果。方法 100例甲亢患者作为研究对象,随机分成研究组与对照组,各50例。对照组患者采取甲巯咪唑或者丙基硫氧嘧啶进行临床治疗,研究组患者给予~(131)I进行临床治疗,比较两组患者临床疗效、甲状腺功能减退(甲减)情况、甲亢复发情况及不良反应的发生情况。结果研究组患者治愈42例,好转5例,无效3例,总有效率为94%,对照组患者治愈30例,好转9例,无效11例,总有效率为78%,研究组总有效率明显高于对照组,比较差异具有统计学意义(P<0.05)。甲减发生率明显高于对照组,不良反应的发生率和复发率明显低于对照组,比较差异均具有统计学意义(P<0.05)。结论对于甲亢患者采取~(131)I进行治疗更加安全有效,这种疗法的综合临床疗效要好于抗甲状腺药物,值得在临床上推广应用。
Objective To investigate the follow-up effect of ~ (131) iodine (~ (131) I) in patients with hyperthyroidism (hyperthyroidism). Methods 100 patients with hyperthyroidism as research object, were randomly divided into study group and control group, 50 cases each. Patients in the control group were treated with methimazole or propylthiouracil. Patients in the study group were given ~ (131) I for clinical treatment. The clinical efficacy, hypothyroidism (hypothyroidism), recurrence of hyperthyroidism Adverse reactions occurred. Results In the study group, 42 cases were cured, 5 cases were improved, 3 cases were ineffective, and the total effective rate was 94%. In the control group, 30 cases were cured, 9 cases were improved, 11 cases were ineffective, and the total effective rate was 78% Significantly higher than the control group, the difference was statistically significant (P <0.05). The incidence of hypothyroidism was significantly higher than that of the control group, the incidence of adverse reactions and relapse rate was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion It is safer and more effective to take ~ (131) I for patients with hyperthyroidism. The comprehensive clinical efficacy of this therapy is better than that of anti-thyroid drugs, which is worth popularizing in clinic.