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Oxide inclusions widely exist in additively manufactured components due to the native oxide layer on the powder surface,together with gas impurities during the printing process.Using in-situ tensile tests combined with electron backscatter diffraction (EBSD) and electron channeling contrast imaging (ECCI)techniques,we propose an asymmetrical cracking mechanism around the oxide inclusions in a selec-tive laser melted 316L stainless steel.The heterogeneous sub-micro cellular structures lead to different twinning tendencies around the inclusions due to the size-related critical twinning stresses,and the deformation-induced nano-twin clusters can resist the cracking propagation,therefore resulting in the asymmetrical cracking behaviors around the inclusions.