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目的:观察针灸联合普罗布考对颈动脉粥样硬化斑块的影响。方法:将80例患者随机分为治疗组和对照组各40例。通过治疗前后颈动脉彩超的测定,观察2组患者颈动脉粥样硬化斑块消退情况,并计算斑块的厚度和面积。结果:消退率治疗组为51.5%,对照组为19.3%,2组比较,差异有显著性意义(P<0.05)。治疗后治疗组斑块厚度明显降低,面积缩小,与治疗前比较,差异均有非常显著性意义(P<0.01),对照组厚度也有减低(P<0.05),但面积缩小不明显。2组比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。结论:针药结合比单纯药物治疗可更好的改善颈动脉粥样硬化斑块情况,进而有助于减轻和防止缺血性脑血管病的发生和发展。
Objective: To observe the effect of acupuncture combined with probucol on carotid atherosclerotic plaque. Methods: 80 patients were randomly divided into treatment group and control group, 40 cases each. Carotid color Doppler echocardiography was performed before and after treatment to observe the regression of carotid atherosclerotic plaque in two groups and to calculate the thickness and area of plaque. Results: The regression rate was 51.5% in the treatment group and 19.3% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the thickness of the plaque in the treatment group was significantly reduced and the area was reduced. Compared with before treatment, the difference was significant (P <0.01). The thickness of the control group was also decreased (P <0.05), but the area was not reduced obviously. The difference between the two groups was significant or very significant (P <0.05, P <0.01). Conclusion: Acupuncture combined with drug treatment can better improve the carotid atherosclerotic plaque, and then help to reduce and prevent the occurrence and development of ischemic cerebrovascular disease.