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目的探讨左氧氟沙星治疗下呼吸道感染患者的临床疗效。方法选取2013年1月至2015年1月长春理工大学医院校医院收治的230例下呼吸道感染患者为研究对象,按随机数字表法将其分为观察组和对照组,各115例。对照组患者给予头孢哌酮钠舒巴坦钠治疗,观察组患者采用盐酸左氧氟沙星注射液治疗,比较两组患者的临床疗效、症状体征消失时间及不良反应发生情况。结果观察组患者的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患者的咳嗽咳痰、胸痛、呼吸气促消失时间均明显短于对照组,差异均有统计学意义(均P<0.05)。结论左氧氟沙星治疗下呼吸感染临床疗效明显,可明显改善患者的临床症状,安全性高。
Objective To investigate the clinical efficacy of levofloxacin in the treatment of patients with lower respiratory tract infection. Methods From January 2013 to January 2015, 230 patients with lower respiratory tract infection admitted to Changchun University of Science and Technology Hospital were enrolled in this study. Each group was divided into observation group and control group by random number table (115 cases). Patients in the control group were given cefoperazone sodium and sulbactam sodium. Patients in the observation group were treated with levofloxacin hydrochloride injection. The clinical efficacy, the disappearance of symptoms and signs and the incidence of adverse reactions were compared between the two groups. Results The total effective rate of the observation group was significantly higher than that of the control group (P <0.05). The cough and sputum, chest pain, and the disappearance of breathlessness in the observation group were significantly shorter than those in the control group Statistical significance (all P <0.05). Conclusion Levofloxacin has obvious clinical efficacy in treating lower respiratory infection, which can significantly improve the clinical symptoms and safety of patients.